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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WNT5B All Species: 39.7
Human Site: T274 Identified Species: 72.78
UniProt: Q9H1J7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1J7 NP_110402.2 359 40323 T274 N S R F T Q P T P E D L V Y V
Chimpanzee Pan troglodytes Q2QLE7 360 40426 T264 N E R F K K P T K N D L V Y F
Rhesus Macaque Macaca mulatta XP_001117880 429 46995 T344 N S R F T Q P T P E D L V Y V
Dog Lupus familis XP_541837 360 40483 T275 N S R F N S P T T Q D L V Y I
Cat Felis silvestris
Mouse Mus musculus P22726 359 40325 T274 N S R F N Q P T P E D L V Y V
Rat Rattus norvegicus Q9QXQ7 380 42265 T295 N S R F N S P T T Q D L V Y I
Wallaby Macropus eugenll
Platypus Ornith. anatinus Q07DZ8 361 40096 T265 N K R F K K P T K N D L V Y F
Chicken Gallus gallus P49337 351 38945 T266 N S Q F K P H T D E D L V Y L
Frog Xenopus laevis P33945 360 40662 T275 N Q R F N P P T G E D L V Y L
Zebra Danio Brachydanio rerio Q92050 363 41119 T278 N N R F N P P T G E D L V Y I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397473 422 46971 T337 D P R F S L P T A N D L V Y L
Nematode Worm Caenorhab. elegans P34889 360 40418 L275 K E R K T R A L P T D L V F M
Sea Urchin Strong. purpuratus XP_779946 415 46408 T330 D A R F N K P T R D D L V Y L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.5 74.1 80.2 N.A. 94.1 76.8 N.A. 48.7 48.1 83.6 79.6 N.A. N.A. 52.1 45.5 55.6
Protein Similarity: 100 63.3 78.3 89.1 N.A. 97.7 85 N.A. 63.7 62.9 91.1 89.2 N.A. N.A. 65.6 66.9 68.6
P-Site Identity: 100 60 100 66.6 N.A. 93.3 66.6 N.A. 60 60 66.6 66.6 N.A. N.A. 53.3 40 53.3
P-Site Similarity: 100 66.6 100 80 N.A. 93.3 80 N.A. 66.6 73.3 73.3 80 N.A. N.A. 73.3 60 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 8 0 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 0 0 0 0 0 0 0 8 8 100 0 0 0 0 % D
% Glu: 0 16 0 0 0 0 0 0 0 47 0 0 0 0 0 % E
% Phe: 0 0 0 93 0 0 0 0 0 0 0 0 0 8 16 % F
% Gly: 0 0 0 0 0 0 0 0 16 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 24 % I
% Lys: 8 8 0 8 24 24 0 0 16 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 8 0 8 0 0 0 100 0 0 31 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 77 8 0 0 47 0 0 0 0 24 0 0 0 0 0 % N
% Pro: 0 8 0 0 0 24 85 0 31 0 0 0 0 0 0 % P
% Gln: 0 8 8 0 0 24 0 0 0 16 0 0 0 0 0 % Q
% Arg: 0 0 93 0 0 8 0 0 8 0 0 0 0 0 0 % R
% Ser: 0 47 0 0 8 16 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 24 0 0 93 16 8 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 24 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 93 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _